A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Radiobiology and Nuclear Medicine".
Deadline for manuscript submissions: 31 December 2022
Special Issue Editors
Cancer is the first or second most common cause of death. Unfortunately, in the next 50 years, the global number of cancer patients is expected to rise. In this sense, there is a need for more effective and selective therapies. Boron neutron capture therapy (BNCT) is a very promising tumor-selective particle radiotherapy. It involves the preferential accumulation of boron carriers in tumor cells, followed by irradiation with a thermal or epithermal neutron beam. Overall BNCT clinical results to date show therapeutic efficacy, associated with an improvement in patient quality of life and prolonged survival. Radiobiological BNCT studies have been of utmost importance to make progress in BNCT, which are also essential to design novel, safe, and effective clinical BNCT protocols (https://isnct.net/).
The aim of this Special Issue is to collect the latest BNCT radiobiological findings performed in in vivo and in vitro experimental models. We also encourage the authors to submit their latest results in the BNCT clinical veterinary field. Contributions should be related to, but not limited to, the study of BNCT for different pathologies, BNCT combined with other cancer therapies, findings related to the radiobiological mechanisms induced by BNCT, the evaluation of new boron compounds, and strategies that could enhance BNCT therapeutic effect and reduce toxicity. We encourage authors to contribute radiobiological findings in the more recently developed area of accelerator based-BNCT, but of course also welcome contributions in the well-established area of reactor-based BNCT.
Looking forward to receiving many valuable contributions.
Dr. Andrea Monti Hughes
Dr. Silva Bortolussi
Dr. Amanda Schwint
Manuscript Submission Information
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boron neutron capture therapy
clinical veterinary studies